Wednesday, 24 July 2013

Advanced Molecular Biology and Genetics

In advanced molecular biology and genetics, the genome is the whole of an organism’s hereditary information. It is encoded either in DNA, or, for several types of viruses, in RNA. The genome takes in both the genes and the non-coding sequences of the DNA/RNA. 

Genome Repair describes how the genome of the bacterium Deinococcus radiodurans gets reassembled after being crushed by-dose radiation. 

Repair of DNA damage is vital for protection against cancer and other age related diseases. Such diseases are supposed to be started by mutations and rearrangements of the DNA sequence. DNA damage produced by ionising radiation, simple alkylating agents or endogenously hydrolytic and oxidative processes is repaired by the base excision repair (BER) pathway.

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